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Animal Breeding, Genetics, & Genomics

Porcine SNP chip development consortium

The Swine Genome Sequencing Consortium (SGSC), recently developed a high density(~60K) SNP chip for pigs. SNP stands for single nucleotide polymorphism. An SNP chip is a microscope slide on which DNA sequences are immobilized and is used by researchers to detect the presence of SNPs. It helps detect variation in DNA components between different individuals.

This high density SNP chip will be employed widely by the porcine research community to drive gene discovery and associated analyses and eventually whole genome selection. The SNPs included for this project were selected from public databases on February 1, 2008.

The SNP chip was first sold by Illumina in 2008 and genotyping is well underway on many projects around the US. Results from the first association trials are expected in late 2009. Preliminary results look excellent and new gene discoveries are expected.

The Swine Genome Sequencing Consortium involves NIFA, the USDA's Agricultural Research Service, the University of Illinois, Iowa State University, and the National Pork Board. Sequencing of the pig genome continues on schedule with completion expected in late 2009. For more information please contact the NRSP-8 Swine Genome Coordinator, Dr. Max Rothschild, at mfrothsc@iastate.edu

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