Zoonotic Disease Risk in Poultry Production - IFSN Seminar
Dr. Melha Mellata, Iowa State University presented a seminar entitled “Can E. coli from contaminated poultry food products cause human extra-intestinal infections? Development and evaluation of a vaccine to improve poultry health and enhance food safety”. This seminar was given via Adobe Connect at 10:00 a.m. EST December 11 and was approved by the Commission on Dietetic Registration for 1.5 Continuing Professional Education Units (CEU).*
This seminar is part of the Institute of Food Safety and Nutrition (IFSN) Seminar Series. These monthly seminars aim to disseminate new knowledge; engage with partners and stakeholders; and inspire the next generation of food safety and nutrition experts. For full information on the series, visit the seminar webpage.
Over 75% of emerging infectious diseases affecting humans can be traced to animals. Most are the result of infections with enteric pathogens, with E coli and Salmonella being important human pathogens, causing substantial infections worldwide. In addition to causing human diseases, bacteria extra-intestinal pathogenic (E. coli) (ExPEC) also infect chickens and cause significant economic losses to the poultry industry, a predominant component of U.S. agriculture. Moreover, chickens are now suspected as a source of ExPEC that cause disease in humans, yet still dismissed as a danger to food production. Likewise, Salmonella enterica infections are a significant public health concern worldwide. Resistance to antibiotics among these bacteria complicates the therapeutic management of their infections. As a result, new treatments and prevention methods (for example, vaccines) are needed to prevent bacterial infections and increase food safety in the future. I will present an overview of our recent USDA-NIFA funded project from my research group that aims to 1) increase understanding of the virulence mechanisms of ExPEC to facilitate development of treatments and preventative measures against infections and contamination; 2) advance the understanding of the zoonotic risk posed by ExPEC in poultry products; and 3) develop and evaluate a Salmonella-based vaccine expressing ExPEC antigens to protect against ExPEC infections in chickens to eliminate their presence in chicken products and/or transmission through the food chain to humans. Success will provide improved human and poultry health, an economic benefit to producers and enhance food safety.
*Registered Dietitian Nutritionists (RDNs) or Nutrition and Dietetics Technicians, Registered (NDTRs) who view this recorded seminar and wish to receive the CEU certificate please e-mail Mallory M. Koenings